[Histonet] eosinophilic crystals in mouse lung answer
Gayle Callis
gcallis <@t> montana.edu
Fri Apr 9 11:49:06 CDT 2004
Dear All,
The question has been answered by Dr. JoAnn Schuh, and much appreciated.
She wrote:
Eosinophilic crystals in mouse lungs are not an artefact. The crystals
form from an endogenous protein, YM-1, that is an autocrystallizing
protein. These crystals in the lung, and a related crystal-forming
protein (YM-2) in the gastrointestinal tract are most frequent in
certain strains of mice (C57BL/6, 129, SW, etc.) and generally are
associated with lung or gastrointestinal injury, respectively. FYI, I
have attached a publication on the characterization of these crystals in
the lungs.
Best regards,
JoAnn
She also attached a pdf of publication and if anyone is interested via
private email.
Gayle Callis
MT,HT,HTL(ASCP)
Research Histopathology Supervisor
Veterinary Molecular Biology
Montana State University - Bozeman
PO Box 173610
Bozeman MT 59717-3610
406 994-6367 (lab with voice mail)
406 994-4303 (FAX)
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